- Tadalafil acts as an active ingredient in Tadalista pills. Tadalista is taken one hour before sex. The effect lasts for 36 hours after taking it. Are the popular pills for ED? Which improves your sex life and helps to enjoy sex longer. This is one of the best drugs used by men. Tadalista should be used only once a day. Otherwise, side effects may occur. Tadalista should be kept away from small children.