Vidalista 80 generally starts working within 30 minutes to an hour after ingestion. However, it’s important to note that sexual stimulation is still necessary for the medication to be effective. Vidalista 80 contains tadalafil, which works by increasing blood flow to the penis during sexual stimulation, helping men achieve and maintain an erection.  Like other tadalafil medications, Vidalista 80 has a longer duration of action compared to some other ED medications.