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- Malegra 100 is a drug that is used to treat erectile dysfunction. The main ingredient in sildenafil is found inside this drug. This drug relaxes the muscles in the penis and therefore arouses sexual arousal for intercourse and erection lasts longer. You should take this medicine only once a day. This drug can be taken 30 minutes before intercourse. This medicine should not be taken broken down or soaked in water. Visit our store mediscap for more information.