Home › Forums › Ask a question › What are the potential drug interactions with Zenegra 100 Mg?
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July 23, 2024 at 12:21 pm #465495
Zenegra 100 mg, which contains Sildenafil Citrate, can interact with several other medications and substances. Here are some potential drug interactions to be aware of:
Nitrates: Sildenafil should not be used in combination with nitrates (e.g., nitroglycerin, isosorbide dinitrate) used to treat angina or other heart conditions. The combination can cause a severe drop in blood pressure.
Alpha-Blockers: Medications used for high blood pressure or benign prostatic hyperplasia (BPH), such as tamsulosin or prazosin, can interact with Zenegra 100 mg. The combination may lead to a significant drop in blood pressure, causing dizziness or fainting.
Antihypertensives: Other blood pressure medications, such as beta-blockers or calcium channel blockers, can also interact with Zenegra 100 mg, potentially enhancing its blood pressure-lowering effects.
Antifungal Medications: Drugs such as ketoconazole and itraconazole can increase the levels of Zenegra 100 mg in the blood by inhibiting its metabolism, potentially leading to an increased risk of side effects.
Antibiotics: Certain antibiotics, like erythromycin and clarithromycin, can affect the metabolism of Sildenafil, potentially increasing its concentration and risk of side effects.
HIV Protease Inhibitors: Medications used to treat HIV, such as ritonavir and saquinavir, can increase Sildenafil levels, leading to a higher risk of adverse effects.
Grapefruit Juice: Grapefruit juice can inhibit the metabolism of Sildenafil, leading to increased levels of the drug in the bloodstream and a higher risk of side effects.
Other Erectile Dysfunction Medications: Combining Sildenafil with other PDE5 inhibitors (e.g., tadalafil, vardenafil) is not recommended as it can increase the risk of side effects.
Riociguat: Riociguat, a medication used to treat pulmonary hypertension, can interact with Sildenafil and may increase the risk of hypotension (low blood pressure).
Always inform your healthcare provider of all the medications, supplements, and substances you are taking before starting Zenegra 100 mg. They can help manage potential interactions and adjust dosages as needed to ensure safe and effective use.
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